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FAQ: FamilyTreeDNA Big Y-700 White Paper


  • FAQ: FamilyTreeDNA Big Y-700 White Paper

    A father passes down a near-exact copy of his chromosome Y (chrY) to his son. Imperfections during replication result in slight differences (e.g. single nucleotide polymorphisms; SNPs) that may be unique to the son. Genealogists use these patterns of similarities and differences to reconstruct paternal ancestry (the Y-tree). The FamilyTreeDNA team (FTDNA) released Big Y in 2013 to provide these patterns directly to customers. At that time, there were thousands of SNPs on the Y-tree connecting hundreds of men [1]. Since then, tens of thousands of men have been studied, and hundreds of thousands of SNPs have been identified. In 2018, armed with this information, updates to the genomic reference sequence [2], and expansion of the Y-tree, FTDNA decided to replace Big Y with a product that would account for updated knowledge of genealogically important regions and increase the overall coverage of chrY. Link to PDF
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